Description

This session will provide an overview of extracorporeal membrane oxygenation (ECMO) circuits and how hemostasis is maintained. First, Dr. Tom Brogan will discuss the common indications for the use of veno-venous (VV) and veno-arterial (VA) ECMO. Dr. Jennifer Muszynski will be speaking about her work on studying transfusion thresholds in ECMO. Transfusion practice for patients on ECMO is variable, but in general these patients are noted to have high transfusion needs due to bleeding, phlebotomy, and high transfusion thresholds. Finally, Dr. Wayne Chandler will describe his research on the mechanism of bleeding and clot formation in ECMO circuits including the role of microparticles as well as provide a practical guide to laboratory testing for anticoagulation management on ECMO.

Learning Objectives:

• Describe common indications for the use of veno-venous(VV) and veno-arterial (VA) extracorporeal membrane oxygenation (ECMO).
• Name 3 factors that account for the significant transfusion requirements for patients on ECMO.
• Interpret laboratory tests for monitoring hemostasis in patients on ECMO.

Speaker(s):

• Tom V Brogan, MD, Seattle Children's Hospital
• Wayne Chandler, MD, Seattle Children's Hospital; University of Washington
• Jennifer A Muszynski, MD, MPH, The Research Institute at Nationwide Children's Hospital; Nationwide Children's Hospital
• Nabiha H. Saifee, MD, PhD, Seattle Children's Hospital; Dept of Laboratory Medicine, University of Washington; Bloodworks NW