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2018 Annual Meeting On-Demand


2018 AM On-Demand: Session SN2-14-SS-2018: Chimeric Antigen Receptor T Cell Therapy for Non-Malignant Conditions


Oct 20, 2018 10:30am ‐ Oct 20, 2018 12:00pm

Expiration Date: Dec 31, 2020


Credits: None available.

Description

This program is available until December 31, 2020.

Program Chair: Suzanne Thibodeaux, MD, PhD
Speakers: Sarita Joshi, MD, MBBS; Vijay Bhoj, MD, PhD; Suzanne Thibodeaux, MD, PhD
Intended Audience: Physician, Medical Director, Manager, Director, Research Scientist, Residents/Fellow, Student (MD, MT, SBB), Supervisor
Teaching Level: Intermediate

Learning Objectives:

  • Review chimeric antigen receptor (CAR) T cell structure, function and current clinical applications
  • Discuss development of CAR T cells for autoimmune diseases
  • Describe efforts to utilize CAR T cells for infectious diseases

Description: Chimeric antigen receptor (CAR) T cells, T cells genetically modified to express a hybrid receptor combining B cell receptor specificity with the activation capacity of a T cell receptor, have gained much visibility given their success in treating malignant conditions, especially hematologic malignancies, with otherwise poor prognoses. Given the recent approval by the Food and Drug Administration (FDA) of CAR T cells directed towards CD19 for acute lymphoblastic leukemia (ALL) and diffuse large B cell lymphoma (DLBCL), the status of CAR T cells as a therapeutic option for malignant conditions is recognized. Motivated by this success, efforts to expand the application of this innovative platform of cellular immunotherapy to other conditions are underway. CAR T cells are being developed for use in such conditions as debilitating autoimmune disease, infectious diseases, such as HIV, and in the setting of organ transplantation. This session will focus on exciting developments that attempt to push the potential clinical applications of CAR T cells beyond the sphere of oncology.

Speaker(s):

Disclosures

  • Vijay Bhoj, MD, PhD :

    Nothing to Disclose

  • Sarita Joshi, MD, MBBS :

    Nothing to Disclose

  • Suzanne Thibodeaux, MD, PhD :

    Nothing to Disclose

Credits

  • 1.25 - General Continuing Education (GEN)
  • 1.25 - Florida Lab Personnel (FLP)
  • 1.25 - California Nurse (CN)
  • 1.25 - California Lab Personnel (CLP)

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