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On-Demand eCasts

20EL-528 On-Demand eCast: Repeat Antibody Screens: What is the Appropriate Interval?

Expiration Date: Apr 28, 2023

Credits: None available.

Please note: AABB reserves the right to make updates to this program.

Live Program Date: April 29, 2020
Master Program Number: 20EL-528

Educational Track: Technical/Clinical
Topic: Transfusion Medicine
Intended Audience: Directors, Hospitals, Hospital Blood Banks, Immunohematology Reference Labs (IRL’s), Laboratory Staff, Managers/Supervisors, Medical Directors, Nurses, Physicians, Research Scientists, Residents/Fellows, Scientists, Students (MD, MT, SBB), Technologists, Transfusion Safety Officers
Teaching Level: Intermediate to Advanced

(titles and affiliations at the time of the live program)
Director/Moderator: Geoffrey Wool, MD, PhD, Assistant Professor, Department of Pathology, Medical Director of Coagulation Laboratory, Attending, Transfusion Medicine/Apheresis Service, Director, Blood Banking/Transfusion Medicine Fellowship Program, University of Chicago, Chicago, IL
Christopher A. Tormey, MD, Associate Professor of Laboratory Medicine and Lecturer in Molecular Biophysics and Biochemistry, Yale University; Medical Director, Transfusion Medicine Service, Laboratory Medicine, Yale-New Haven Hospital; Director, Transfusion Medicine Fellowship, Yale School of Medicine, New Haven, CT

Learning Objectives

After participating in this educational activity, participants should be able to:

  • Describe kinetics of antibody development, including evanescence and anamnestic response.
  • Apply principles of immunoglobulin production to policy development for antibody screen expiration.
  • Identify situations where the extension of antibody screen expiration date could increase patient risk for hemolytic reaction

Program Description: Antibody screens are generally repeated every three days in recently transfused or pregnant patients, given the risk of new antibody formation. In patients without recent transfusion or pregnancy, the interval between antibody screens can be extended and this is typically convenient for pre-operative patients distant from the hospital. However, the optimal time to extend expiration time in select patient populations is not known. This eCast will also discuss the timing of antibody development and evanescence, as they impact compatibility testing.

How to Claim CE Credit

  • Single Viewers: if you registered as a single viewer, complete the evaluation found on the "CE Information" tab after watching the video. By submitting the evaluation, you are attesting to watching the presentation in its entirety.
  • Group Viewers: This is applicable for groups/facilities that purchased Group Viewing access for this program (registration will be verified prior to processing a group viewing attendance log). Group Viewing Coordinators should submit the attendance log to eLearning@aabb.org within 72 hours of the completion/viewing date. Once AABB receives an attendance log, each participant on the attendance log will be granted access as a single viewer to this program and will be required to complete the evaluation in order to claim continuing education credit. Each participant will be required to have an AABB account in order to access this program/platform. If a participant does not have an account, he/she can create one using the same email address provided on the attendance log.

Director & Moderator(s):


By completing the evaluation, you are attesting to watching the presentation in its entirety. A certificate will be immediately provided after submission.


  • 1.00 - General Continuing Education (GEN)
  • 1.00 - Florida Lab Personnel (FLP)
  • 1.00 - California Lab Personnel (CLP)