Oxygen (O2) homeostasis is critically intertwined with erythropoietic response in blood loss and anemia and the hormones that modulate iron mobilization and RBC production are intriguing markers for the monitoring of transfusion effectiveness in acute and chronic settings. Further, minimally invasive O2 measurements offer a greater understanding of tissue specific adaptation to anemia and response to transfusion. The speakers will guide the audience through physiological adaptive responses to anemia, novel modalities to assess oxygen hemostasis and imbalance and considerations for clinically feasible application toward optimizing transfusion efficacy.
Explain the basic science that defines red blood cell communication and tissue adaptive response to hypoxia during anemia.
Discuss novel technologies that are adaptable to the assessment of tissue oxygenation pre- and post-transfusion.
Differentiate clinically useful approaches to assessing oxygen homeostasis toward guiding transfusion needs during anemia.