Therapeutic apheresis is applied to patients with a spectrum of organ and life-threatening diseases in both the inpatient and outpatient settings. While the positive impact of apheresis therapy is recognized, meaningful clinical studies in apheresis medicine are challenging to perform. In this informative and interactive session, three past presidents of the American Society for Apheresis will discuss the trials and tribulations of performing significant investigations in apheresis medicine, as well as review apheresis studies that they believe have been the most meaningful to the field. Consequential studies that are actively underway in therapeutic apheresis that have the potential to alter current practices, as well as those trials which should be conducted, will also be discussed. Therapeutic apheresis interventions to be analyzed include therapeutic plasma exchange, red cell exchange, extracorporeal photopheresis, LDL-apheresis, and therapeutic cytapheresis. An exciting panel discussion involving the audience about needed future investigations, barriers to involvement in clinical trials, and opportunities for collaboration will follow the presentations by these past presidents.
Explain the challenges in performing clinical studies in therapeutic apheresis.
Recognize the most impactful studies involving therapeutic plasma exchange, red cell exchange, extracorporeal photopheresis, LDL-apheresis, and therapeutic cytapheresis.
Identify therapeutic apheresis studies that are currently underway, as well as those needing to be performed, that have the potential to significantly influence the practice of apheresis medicine.