Run time: 68m

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2020 AABB Annual Meeting On-Demand

AM20-74: Case Studies in Extracorporeal Life Support

Oct 5, 2020 9:00pm ‐ Oct 5, 2020 9:00pm

Expiration Date: Dec 31, 2022

Credits: None available.

Standard: $25.00
Members: $20.00


Through a series of case studies, this session will demonstrate strategies to manage hemostasis in patients on extracorporeal life support (ECLS) as well as identify gaps in knowledge that require further research. Cases will provide a practical guide to interpretation of laboratory testing for anticoagulation management, discuss traditional and alternative treatments for bleeding and DIC, and explain utility of plasma exchange in patients on ECLS. Scenarios will include discordant laboratory testing for heparin monitoring, bleeding in patients on alternative anticoagulants such as direct thrombin inhibitors (bivalirudin and argatroban), treatment of acquired von Willebrand disease, alternative treatments for bleeding such as nebulized or intrapulmonary antifibrinolytics, plasma exchange for patient with severe hemolysis or need for hemostasis reset, and treatment of purpura fulminans on ECLS. Additional cases will demonstrate transfusion needs on ECLS with discussion of research on RBC and platelet loss in the ECLS circuits. Finally, a visual case series will show the histologic structure and location of thrombi in ECLS circuits in a variety of scenarios providing insight into the mechanism of clot formation.

Learning Objectives:
  • Interpret tests utilized for monitoring anticoagulation on extracorporeal life support (ECLS) circuits
  • Name 3 factors that account for the significant transfusion requirements for patients on ECLS
  • Apply alternative treatments other than blood component therapy for bleeding on ECLS



  • Lisa Hensch, MD : Nothing to disclose
  • Nabiha Saifee, MD, PhD : Nothing to disclose
  • Poyyapakkam Srivaths, MD : Nothing to disclose

Credits Available

AM20-74: Case Studies in Extracorporeal Life Support Evaluation

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