Decreasing platelet donors and increasing usage due to an aging population with losses due to new sampling requirements for bacteria detection may lead to shortages. Recent changes to deferral policies (e.g.,12 to 3 months) speak to the need to retain more donors. Pathogen reduction technologies (PRT) could allow further deferral relaxation (e.g., deferrals for men who have had sex with other men or travel to malaria endemic countries) and replacement of screening to increase platelet and plasma availability. To maintain blood supply continuity amid emergence of transfusion-transmitted diseases and in times of disaster, preparedness plans including rapid scalability of PRT for the platelet and plasma supply to allow for temporary deferral relaxation and increased production would be required. The session concludes considering PRT as part of business continuity plans of blood centers and hospitals to avoid critical shortages.
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Evaluate why the current state of the platelet supply is at risk of critical shortages.
Apply a multifaceted approach, including changes and relaxation of some deferral policies with the use of PRT, building the flexibility needed during times of disaster to grow the donor pool and increase production of plasma and platelets.
Prepare business continuity plans for hospitals and blood centers in case an agent is transfusion-transmissible and using PRT to avoid critical shortages.