This session will illustrate how to leverage lab information system (LIS) and electronic health record (EHR) tools for communication and control of hematopoietic progenitor cell transplant (HPCT) recipient transfusion needs and will be applicable to multiple lab information and electronic health record systems. The session will also include an introduction to transfusion support for HPCT recipients. Examples of EHR designs will demonstrate how to streamline blood ordering processes to limit frequent addition or removal of special attributes and communicate transfusion needs. We will also present LIS-based solutions to hardwire selection of red blood cell and plasma-containing products based on donor and recipient ABO types and allow for safe electronic crossmatch. Potential software limitations will also be discussed.