The US MSM deferral was reduced from “if even one time since 1977” in 2018 to 12 months, and in 2020 3 months. A few countries such as Italy and Spain have alternative criteria (no MSM deferral). In France and Israel MSM donate plasma with quarantine. In December 2020 a group supported by the Forum representing the four UK blood services “For the Assessment of Individual Risk (FAIR)” reported that a more individualized approach to donor selection policy was feasible in the UK. This was accepted by health ministers and is expected to be implemented in the summer of 2021. In the US, the Assessing Donor Variability And New Concepts in Eligibility (ADVANCE Study), a pilot study to evaluate behavioral screening questions is in progress. Sponsored by the AABB Donor History Task Force and the ISBT Transfusion Transmitted Infectious Diseases Working Party this session will focus on imminent changes to donor eligibility for MSM in the UK and progress towards revised donor criteria in the US.