Utilizing Smart Storage RFID for manufacturing and inventory control of 48-hour Large Volume Delayed Sampling (LVDS) and Pathogen Reduced (PR) platelets as part of the new Food and Drug Administration Guidance to Industry. The session details planning, validating, and implementing a Smart Storage RFID system in the donor center and hospital. RFID allows for electronic tracking of component manufacturing time frames related LVDS and PR platelets in the donor center, as well as supports the hospital blood bank in managing multiple platelet inventories and selection of platelets for use in transfusion. The risk/cost benefit of implementing RFID includes monetary and intellectual allocation to innovation that is used in the non-pharmaceutical industry and applying this concept to manufacturing, distribution, and inventory control of blood components. Implementation requires a detailed evaluation of current processes to allow for a tailored implementation specific to each unique facility.