The UVM Medical Center was recently the victim of a cyberattack in the midst of a global pandemic. The cyberattack put the entire hospital system into complete downtime procedures for 25 days and left many third party applications disabled for over three months after the attack. It is important to understand the true impact of a cyberattack and to recognize potential strategies for operational and risk-mitigation processes in response to a total and prolonged IT system outage. Based on the experience of a Blood Bank Technical Specialist, a Pathologist, and an Anesthesiologist, participants of this session will learn how the Blood Bank, the general laboratory, the OR, and inpatient units remained nimble, reacted to critical situations not addressed in standard downtime procedures, and implemented creative solutions in order to provide timely and safe patient care. Given the increasing number of cyberattacks targeting healthcare services, now is the time to consider how your hospital can prepare for the very real threat of living through one.