The COVID-19 pandemic brought the need to keep people separated, either to quarantine or decrease viral transmission. In some settings, remote work solutions were already partly utilized and had to be expanded, and in other cases, completely new telehealth solutions were implemented to meet the continuing and growing work demands in transfusion and blood banking. Overall, the global pandemic quickly forced universal adoption of these tools to facilitate social distancing. While some technology solutions improved workflows and efficiency, these implementations also provided their own challenges. The technology tools range from video conferencing to chat tools to remote system access. We review these tools and implementation considerations as well as case studies of remote work in action.