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On-Demand eCasts

22EL-732 On-Demand eCast: Immunohematology Boot Camp: RH Variants

Expiration Date: May 9, 2025

Credits: None available.

Live Program Date: Wednesday, May 11, 2022
Program Number: 22EL-732

Educational Track: Technical/Clinical
Topic: Patient Transfusion
Intended Audience: Facilities that perform molecular testing, Hospital Blood Banks, Immunohematology Reference Labs (IRL’s), Laboratory Staff, Managers/Supervisors, Medical Directors, Residents/Fellows

(titles and affiliations at the time of the live program)
Director/Moderator: Lynsi Rahorst, MHPE, MT(ASCP)SBBCM, Manager, Education & Training IRL/Genomics, New York Blood Center Enterprises, Kansas City, MO
Speakers: Gorka Ochoa-Garay, MD, PhD, Director of Bioinformatics and Assay Development, New York Blood Center, Long Island City, NY; Sunitha Vege, MS, Technical Director, Genomics Laboratory, New York Blood Center, Long Island City, NY

Program Description
Over the past decades, the number and our understanding of altered RH alleles has increased significantly. While serologic methods were initially used to describe altered Rh phenotypes, molecular methods have provided an explanation for the altered expression of Rh antigens. In addition, they have uncovered over 1,000 RH alleles in various human populations. Understanding the genetic mechanisms that lead to altered RH alleles and the currently available detection methods can improve selection of blood for transfusion.

In this program, the faculty will review the transfusion challenges presented by patients with altered RH alleles and discuss case studies that exemplify the strengths and limitations of current testing strategies.

Learning Objectives
After participating in this educational activity, participants should be able to:

  • Describe the challenges associated with the transfusion of patients with altered RH alleles.
  • Identify the common genetic mechanisms that lead to altered RH alleles.
  • Discuss the molecular methods utilized to identify RH alleles, including their strengths and limitations.
  • Discuss case studies involving complex RH alleles and make transfusion recommendations.

How to Claim Continuing Education Credit

  • Single Viewers: if you registered as a single viewer, complete the evaluation found on the "CE Information" tab after watching the video. By submitting the evaluation, you are attesting to watching the presentation in its entirety.
  • Group Viewers: This is applicable for groups/facilities that purchased Group Viewing access for this program (registration will be verified prior to processing a group viewing attendance log). Group Viewing Coordinators should submit the attendance log to eLearning@aabb.org within 72 hours of the completion/viewing date. Once AABB receives an attendance log, each participant on the attendance log will be granted access as a single viewer to this program and will be required to complete the evaluation in order to claim continuing education credit. Each participant will be required to have an AABB account in order to access this program/platform. If a participant does not have an account, he/she can create one using the same email address provided on the attendance log.

Director & Moderator(s):


By completing the evaluation, you are attesting to watching the presentation in its entirety. A certificate will be immediately provided after submission.

All relevant financial relationships have been mitigated.


  • 1.00 - General Continuing Education (GEN)
  • 1.00 - Florida Lab Personnel (FLP)
  • 1.00 - California Nurse (CN)
  • 1.00 - California Lab Personnel (CLP)
  • 1.00 - Physician (PHY)