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On-Demand eCasts

22EL-768 On-Demand eCast: TACO and TRALI: Pulmonary Adverse Effects of Transfusion

Expiration Date: Aug 22, 2025

Credits: None available.


Live Program Date: Wednesday, August 24, 2022
Program Number: 22EL-768

Educational Track: Technical/Clinical
Topic: Hemovigilance, Patient Transfusion
Intended Audience: Hospital Blood Banks, Hospitals, Laboratory Staff, Managers/Supervisors, Medical Directors, Nurses, Perfusionists, Physicians, Residents/Fellows, Students (MD, MT, SBB), Technologists, Transfusion Safety Officers
Teaching Level: Basic, Intermediate

(titles and affiliations at the time of the live program)
Director/Moderator: David Unold, MD, Health Sciences Associate Clinical Professor, UC Davis School of Medicine, Sacramento, CA
Speakers: Pearl Toy, MD, Professor Emeritus, Blood Bank Director Emeritus, Laboratory Medicine, UCSF School of Medicine, San Francisco, CA; Mark Looney, MD, Professor, Medicine and Laboratory Medicine, UCSF School of Medicine, San Francisco, CA

Program Description
Transfusion reactions presenting with pulmonary signs and symptoms are common. While progress has been made in the prevention of Transfusion Related Acute Lung Injury (TRALI), Transfusion Associated Circulatory Overload (TACO) remains a common cause of morbidity. There is difficulty in differentiating between TACO and TRALI given similarities between the two entities and lack of a definitive biomarker for TRALI. Led by a transfusion medicine specialist and a pulmonary/critical care specialist, this program will explore pulmonary transfusion reactions and propose novel considerations regarding this difficult topic. Particularly, the role of clinical specialists in the diagnosis of pulmonary transfusion reactions will be elucidated.

Learning Objectives
After participating in this educational activity, participants should be able to:

  • Differentiate the pathophysiology and diagnosis of Transfusion Related Acute Lung Injury (TRALI) and Transfusion Associated Circulatory Overload (TACO).
  • Report on the progress made in the prevention of TRALI (and what this may imply about reactions currently classified as TRALI).
  • Describe the diagnosis, treatment, and prevention of TACO.
  • Explain the role of clinical specialists in the evaluation of pulmonary transfusion reactions.

How to Claim Continuing Education Credit

  • Single Viewers: if you registered as a single viewer, complete the evaluation found on the "CE Information" tab after watching the video. By submitting the evaluation, you are attesting to watching the presentation in its entirety.
  • Group Viewers: This is applicable for groups/facilities that purchased Group Viewing access for this program (registration will be verified prior to processing a group viewing attendance log). Group Viewing Coordinators should submit the attendance log to within 72 hours of the completion/viewing date. Once AABB receives an attendance log, each participant on the attendance log will be granted access as a single viewer to this program and will be required to complete the evaluation in order to claim continuing education credit. Each participant will be required to have an AABB account in order to access this program/platform. If a participant does not have an account, he/she can create one using the same email address provided on the attendance log.

Director & Moderator(s):

  • David Unold, University of California, Davis School of Medicine



  • 1.00 - General Continuing Education (GEN)
  • 1.00 - Florida Lab Personnel (FLP)
  • 1.00 - California Lab Personnel (CLP)

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