The care and transfusion support of patients undergoing hematopoietic stem cell or solid organ transplant presents a unique challenge when transfusion of blood or blood products is not an option. This is particularly the case for stem cell transplants, where pancytopenia associated with peri-transplant conditioning regimens and post-transplant prior to engraftment. For solid organ transplants, patient optimization is critical at the pre-, intra- and post-operative phases for successful outcomes. Speakers will share experiences managing patients in each of these settings. Agents such as Aminocaproic acid, Romiplostim and others will be discussed, along with proposed protocols for patient management. Optimization strategies in the pre-transplant phase for solid organs will be discussed, along with management strategies including isovolemic hemodilution, intraoperative blood salvage and others. Attendees will share their experiences and strategies to approach this complex situation as well. The exchange of these experiences will provide transfusion medicine physicians with effective strategies to support these complex scenarios.
Summarize and discuss the challenges facing the care of patients who refuse blood and/or blood products in their management, including establishment of clear multidisciplinary communication to ensure appropriate transfusion support management is provided for each patient.
Examine unconventional support strategies to manage patients undergoing hematopoietic stem cell transplants without transfusion of blood or blood products
Illustrate strategies to optimize patients undergoing bloodless solid organ transplants in the pre- intra- and post-operative phases.