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AM21-75: Strategies to Address Critical Stresses on the Platelet Inventory

‐ Oct 17, 2021 7:15pm

Expiration Date: Dec 31, 2023

Credits: None available.

This session will explore ways to increase self-sufficiency of the platelet supply. It will begin with describing the state of the US platelet supply including the decreasing and aging volunteer donor base, and the increasing demand due to aging population with comorbidities. It will then briefly discuss the consideration of paid platelet donors. The session will then move to strategies to improve platelet availability with two presentations. The first will discuss alternative production methods and quality parameters including increasing production of whole blood-derived platelets including buffy coat component manufacture, lowering the platelet dose from 3.0 to 2.5 x 1011/unit, overnight hold of whole blood prior to platelet production and ways to prolong storage time. The second will examine strategies to minimize platelet wastage including cold stored and cryopreserved platelets for bleeding patients including the pros and cons. Question time will focus on audience idea generation.

Learning Objectives:

  • Propose new platelet production approaches to the improvement of platelet inventory.
  • Review novel platelet storage strategies to improve supply and minimize wastage.
  • Describe the current challenges with management of the US platelet inventory.



  • Dana Devine, PhD:
    Scientific Advisory Board: Macopharma; Board of Directors: STRM.Bio; Grant/Research Support: TerumoBCT, Macopharma, Hemanext
  • Denese Marks, PhD:
    Board of Directors: ISBT; Grant/Research Support: Macopharma, Cryogenics Holdings

All relevant financial relationships have been mitigated. By completing the evaluation, you are attesting to watching the presentation in its entirety. A certificate will be immediately provided after submission.

Credits Available

AM21-75: Strategies to Address Critical Stresses on the Platelet Inventory Evaluation