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This is an oral abstract session about RBC Immunology- Mouse Models.
Learning Objectives:
Discuss the possible utility of IgG subclass examination in predicting whether an alloimmune response resulted from primary RBC alloantigen exposure, or repeat exposure
Explore the impact of antigen density on alloimmunization events.
Discuss the potential impact of immune checkpoint immunotherapy in the loss of tolerance resulting in autoimmune hemolytic anemia (AIHA)
Explore the potential role of undetected prior immunity toward intracellular antigens in increased alloimmunization rates within some individuals
Discuss the potential of increased reticulocyte rates as a risk factor for alloimmunization
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