AM24-MN-28-O: Choose Your Own Adventure: Exploring the Depths of Serology and Peaks of Genomics (Enduring)

What do you do when you discover an unexpected antigen typing? Do you investigate history, rule out sample switch, opt for a different serologic technique, or refer for DNA testing? What about when you encounter an antibody of unidentified specificity? Which test do you perform next, and once the antibody is identified, how is clinical relevance determined? When the safety and well-being of the patient are at stake, possibilities can be overwhelming, test results difficult to interpret, and answers elusive. In this interactive session, participants will act as blood bankers and make critical decisions to shape the outcome of complex and uncommon serology and molecular case studies. Key decision paths will be discussed throughout the cases to illustrate the value and limitations of specific serology and molecular methods and to arrive at an accurate interpretation of test results. Blood Bankers will enhance their knowledge of options to consider when unusual results occur for application in future cases. Clinicians will gain insight into various testing approaches to reach appropriate transfusion considerations/ recommendations.