CABP CE Eligible

Hematopoietic stem cells (HSCs) are the apex hematopoietic cell with the potential to produce robust and lifelong production of all blood cells. Thus, understanding the details of HSC molecular biology is critical to our understanding of human health and longevity. Mechanistic insights into HSC biology could be leveraged to further improve the strategies available to maintain and expand functional HSCs in vitro. Overcoming these hurdles is critical to effectively use HSCs for off-the-shelf allogeneic HSC transplantation or gene-editing of autologous HSCs for treatments of hematological disease and malignancies. In this session, we will discuss the most recent applications of HSC expansion technology currently in clinical use. We will also explore the latest mechanistic breakthroughs towards producing abundant HSCs in vitro for use in transfusion applications.

Colleen Delaney

Deverra Therapeutics

Appearances